Загрузка...
Rescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouse.
Increased utrophin expression is known to reduce pathology in dystrophin-deficient skeletal muscles. Transgenic over-expression of PGC-1α has been shown to increase levels of utrophin mRNA and improve the histology of mdx muscles. Other reports have shown that PGC-1α signaling can lead to increased...
Сохранить в:
| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2012-01-01
|
| Серии: | PLoS ONE |
| Online-ссылка: | http://europepmc.org/articles/PMC3256197?pdf=render |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|