Systemic Myostatin Inhibition via Liver-Targeted Gene Transfer in Normal and Dystrophic Mice

BACKGROUND: Myostatin inhibition is a promising therapeutic strategy to maintain muscle mass in a variety of disorders, including the muscular dystrophies, cachexia, and sarcopenia. Previously described approaches to blocking myostatin signaling include injection delivery of inhibitory propeptide do...

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Main Authors: Morine, Kevin J., Bish, Lawrence T., Pendrak, Klara, Sleeper, Meg M., Barton, Elisabeth R., Sweeney, H. Lee
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820101/
https://ncbi.nlm.nih.gov/pubmed/20161803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009176
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