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ACTIVIN IIB RECEPTOR BLOCKADE ATTENUATES DYSTROPHIC PATHOLOGY IN A MOUSE MODEL OF DUCHENNE MUSCULAR DYSTROPHY

Modulation of transforming growth factor-β (TGF-β) signaling to promote muscle growth holds tremendous promise for the muscular dystrophies and other disorders involving the loss of functional muscle mass. Previous studies have focused on the TGF-β family member myostatin and demonstrated that inhib...

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Detalhes bibliográficos
Publicado no:Muscle Nerve
Main Authors: Morine, Kevin J., Bish, Lawrence T., Selsby, Joshua T., Gazzara, Jeffery A., Pendrak, Klara, Sleeper, Meg M., Barton, Elisabeth R., Lee, Se-Jin, Sweeney, H. Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505731/
https://ncbi.nlm.nih.gov/pubmed/20730876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.21743
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