Chronic Losartan Administration Reduces Mortality and Preserves Cardiac but Not Skeletal Muscle Function in Dystrophic Mice

Duchenne muscular dystrophy (DMD) is a degenerative disorder affecting skeletal and cardiac muscle for which there is no effective therapy. Angiotension receptor blockade (ARB) has excellent therapeutic potential in DMD based on recent data demonstrating attenuation of skeletal muscle disease progre...

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Autors principals: Bish, Lawrence T., Yarchoan, Mark, Sleeper, Meg M., Gazzara, Jeffrey A., Morine, Kevin J., Acosta, Pedro, Barton, Elisabeth R., Sweeney, H. Lee
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120761/
https://ncbi.nlm.nih.gov/pubmed/21731628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020856
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