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Chronic Losartan Administration Reduces Mortality and Preserves Cardiac but Not Skeletal Muscle Function in Dystrophic Mice

Duchenne muscular dystrophy (DMD) is a degenerative disorder affecting skeletal and cardiac muscle for which there is no effective therapy. Angiotension receptor blockade (ARB) has excellent therapeutic potential in DMD based on recent data demonstrating attenuation of skeletal muscle disease progre...

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Detalhes bibliográficos
Main Authors: Bish, Lawrence T., Yarchoan, Mark, Sleeper, Meg M., Gazzara, Jeffrey A., Morine, Kevin J., Acosta, Pedro, Barton, Elisabeth R., Sweeney, H. Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120761/
https://ncbi.nlm.nih.gov/pubmed/21731628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020856
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