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Systemic Myostatin Inhibition via Liver-Targeted Gene Transfer in Normal and Dystrophic Mice
BACKGROUND: Myostatin inhibition is a promising therapeutic strategy to maintain muscle mass in a variety of disorders, including the muscular dystrophies, cachexia, and sarcopenia. Previously described approaches to blocking myostatin signaling include injection delivery of inhibitory propeptide do...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820101/ https://ncbi.nlm.nih.gov/pubmed/20161803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009176 |
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