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Spliceosome Structure and Function

Pre-mRNA splicing is catalyzed by the spliceosome, a multimegadalton ribonucleoprotein (RNP) complex comprised of five snRNPs and numerous proteins. Intricate RNA-RNA and RNP networks, which serve to align the reactive groups of the pre-mRNA for catalysis, are formed and repeatedly rearranged during...

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Bibliografski detalji
Glavni autori: Will, Cindy L., Lührmann, Reinhard
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119917/
https://ncbi.nlm.nih.gov/pubmed/21441581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a003707
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