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Structure and function of an RNase H domain at the heart of the spliceosome
Precursor-messenger RNA (pre-mRNA) splicing encompasses two sequential transesterification reactions in distinct active sites of the spliceosome that are transiently established by the interplay of small nuclear (sn) RNAs and spliceosomal proteins. Protein Prp8 is an active site component but the mo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2580788/ https://ncbi.nlm.nih.gov/pubmed/18843295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.209 |
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