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Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31

Human proteins 15.5K and hPrp31 are components of the major spliceosomal U4 snRNP and of the minor spliceosomal U4atac snRNP. The two proteins bind to related 5′-stem loops (5′SLs) of the U4 and U4atac snRNAs in a strictly sequential fashion. The primary binding 15.5K protein binds at K-turns that e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Sunbin, Ghalei, Homa, Lührmann, Reinhard, Wahl, Markus C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162331/
https://ncbi.nlm.nih.gov/pubmed/21784869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2690611
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