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A protein map of the yeast activated spliceosome as obtained by electron microscopy

We have elucidated the spatial arrangement of proteins and snRNP subunits within the purified spliceosomal B(act) complex from Saccharomyces cerevisiae, using negative-stain immunoelectron microscopy. The B(act) spliceosome exhibits a mushroom-like shape with a main body connected to a foot and a st...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Sun, Chengfu, Rigo, Norbert, Fabrizio, Patrizia, Kastner, Berthold, Lührmann, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986897/
https://ncbi.nlm.nih.gov/pubmed/27368340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.057778.116
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