Mitochondrial Phosphatase PTPMT1 is essential for cardiolipin biosynthesis

PTPMT1 was the first protein tyrosine phosphatase found localized to the mitochondria, but its biological function was unknown. Herein, we demonstrate that whole body deletion of Ptpmt1 in mice leads to embryonic lethality, suggesting an indispensable role for PTPMT1 during development. Ptpmt1-defic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Ji, Guan, Ziqiang, Murphy, Anne N., Wiley, Sandra E., Perkins, Guy A., Worby, Carolyn A., Engel, James L., Heacock, Philip, Nguyen, Oanh Kim, Wang, Jonathan H., Raetz, Christian R.H., Dowhan, William, Dixon, Jack E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119201/
https://ncbi.nlm.nih.gov/pubmed/21641550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.04.007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados