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A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4

Cardiolipin (CL), a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes, has pivotal functions for the cellular energy metabolism, mitochondrial dynamics and the initiation of apoptotic pathways. Perturbations in the mitochondrial CL metabolism cause cardiomyopathy in...

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Detalhes bibliográficos
Main Authors: Osman, Christof, Haag, Mathias, Wieland, Felix T, Brügger, Britta, Langer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892375/
https://ncbi.nlm.nih.gov/pubmed/20485265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.98
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