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Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis

PTPMT1 (PTP localized to the Mitochondrion 1) is a member of the protein tyrosine phosphatase superfamily that is localized exclusively to the mitochondrion. We recently reported that PTPMT1 dephosphorylates phosphatidylglycerol phosphate, an essential intermediate of cardiolipin biosynthesis. To ga...

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Главные авторы: Xiao, Junyu, Engel, James L., Zhang, Ji, Chen, Mark J., Manning, Gerard, Dixon, Jack E.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142007/
https://ncbi.nlm.nih.gov/pubmed/21730175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109290108
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