Pharmacological Targeting of the Mitochondrial Phosphatase PTPMT1

The dual-specificity protein tyrosine phosphatases (PTPs) play integral roles in the regulation of cell signaling. There is a need for new tools to study these phosphatases, and the identification of inhibitors potentially affords not only new means for their study, but also possible therapeutics fo...

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Bibliographic Details
Main Authors: Doughty-Shenton, Dahlia, Joseph, James D., Zhang, Ji, Pagliarini, David J., Kim, Youngjun, Lu, Danhong, Dixon, Jack E., Casey, Patrick J.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2010
Subjects:
Endocrine and Diabetes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872949/
https://ncbi.nlm.nih.gov/pubmed/20167843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.163329
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