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Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules
Mice with three amino acid mutations in the calmodulin binding domain of type-2 ryanodine receptor ion channel (Ryr2(ADA/ADA) mice) have impaired intracellular Ca(2+) handling and cardiac hypertrophy with death at an early age. In this report, the role of signaling molecules implicated in cardiac hy...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119098/ https://ncbi.nlm.nih.gov/pubmed/21421818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00719.2010 |
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