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Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules
Mice with three amino acid mutations in the calmodulin binding domain of type-2 ryanodine receptor ion channel (Ryr2(ADA/ADA) mice) have impaired intracellular Ca(2+) handling and cardiac hypertrophy with death at an early age. In this report, the role of signaling molecules implicated in cardiac hy...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119098/ https://ncbi.nlm.nih.gov/pubmed/21421818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00719.2010 |
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