Myosin head orientation: a structural determinant for the Frank-Starling relationship

The cellular mechanism underlying the Frank-Starling law of the heart is myofilament length-dependent activation. The mechanism(s) whereby sarcomeres detect changes in length and translate this into increased sensitivity to activating calcium has been elusive. Small-angle X-ray diffraction studies h...

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Bibliografiset tiedot
Päätekijät: Farman, Gerrie P., Gore, David, Allen, Edward, Schoenfelt, Kelly, Irving, Thomas C., de Tombe, Pieter P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2011
Aiheet:
Muscle Mechanics and Ventricular Function
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119094/
https://ncbi.nlm.nih.gov/pubmed/21460195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01221.2010
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