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Myosin head orientation: a structural determinant for the Frank-Starling relationship
The cellular mechanism underlying the Frank-Starling law of the heart is myofilament length-dependent activation. The mechanism(s) whereby sarcomeres detect changes in length and translate this into increased sensitivity to activating calcium has been elusive. Small-angle X-ray diffraction studies h...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119094/ https://ncbi.nlm.nih.gov/pubmed/21460195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01221.2010 |
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