The Role of Thin Filament Cooperativity in Cardiac Length-Dependent Calcium Activation

Length-dependent activation (LDA) is a prominent feature of cardiac muscle characterized by decreases in the Ca(2+) levels required to generate force (i.e., increases in Ca(2+) sensitivity) when muscle is stretched. Previous studies have concluded that LDA originates from the increased ability of (s...

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Main Authors: Farman, Gerrie P., Allen, Edward J., Schoenfelt, Kelly Q., Backx, Peter H., de Tombe, Pieter P.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2010
Assuntos:
Muscle, Motility, and Motor Proteins
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965940/
https://ncbi.nlm.nih.gov/pubmed/21044595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.003
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