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A Nebulin Ruler Does Not Dictate Thin Filament Lengths

To generate force, striated muscle requires overlap between uniform-length actin and myosin filaments. The hypothesis that a nebulin ruler mechanism specifies thin filament lengths by targeting where tropomodulin (Tmod) caps the slow-growing, pointed end has not been rigorously tested. Using fluores...

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Bibliografiska uppgifter
Huvudupphovsmän: Castillo, Angelica, Nowak, Roberta, Littlefield, Kimberly P., Fowler, Velia M., Littlefield, Ryan S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717268/
https://ncbi.nlm.nih.gov/pubmed/19254544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.053
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