Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1

Cyclin-dependent kinase 1 (Cdk1) is thought to trigger centrosome separation in late G2 phase by phosphorylating the motor protein Eg5 at Thr927. However, the precise control mechanism of centrosome separation remains to be understood. Here, we report that in G2 phase polo-like kinase 1 (Plk1) can t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Smith, Ewan, Hégarat, Nadia, Vesely, Clare, Roseboom, Isaac, Larch, Chris, Streicher, Hansjörg, Straatman, Kornelis, Flynn, Helen, Skehel, Mark, Hirota, Toru, Kuriyama, Ryoko, Hochegger, Helfrid
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2011
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117641/
https://ncbi.nlm.nih.gov/pubmed/21522128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.120
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