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HIF-1α depletion results in SP1-mediated cell cycle disruption and alters the cellular response to chemotherapeutic drugs

Hypoxia inducible factor (HIF) is the major transcription factor involved in the regulation of the cellular response to hypoxia or low oxygen tensions. Even though HIF-1 function is mostly studied following hypoxic stress, well oxygenated areas of several diseased tissues have detectable levels of t...

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Detalhes bibliográficos
Main Authors: Culver, Carolyn, Melvin, Andrew, Mudie, Sharon, Rocha, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117135/
https://ncbi.nlm.nih.gov/pubmed/21412054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.8.15326
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