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The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH
The hypoxia-inducible factor (HIF) is a master regulator of the cellular response to hypoxia. Its levels and activity are controlled by dioxygenases called prolyl-hydroxylases and factor inhibiting HIF (FIH). To activate genes, HIF has to access sequences in DNA that are integrated in chromatin. It...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204077/ https://ncbi.nlm.nih.gov/pubmed/21900490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-02-0163 |
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