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PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia

Hypoxia is an important developmental cue for multicellular organisms but it is also a contributing factor for several human pathologies, such as stroke, cardiovascular diseases and cancer. In cells, hypoxia activates a major transcriptional program coordinated by the Hypoxia Inducible Factor (HIF)...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Mudie, Sharon, Bandarra, Daniel, Batie, Michael, Biddlestone, John, Moniz, Sonia, Ortmann, Brian, Shmakova, Alena, Rocha, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614811/
https://ncbi.nlm.nih.gov/pubmed/25558831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.972889
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