Mechanism of Hypoxia-Induced NF-κB

NF-κB activation is a critical component in the transcriptional response to hypoxia. However, the underlying mechanisms that control its activity under these conditions are unknown. Here we report that under hypoxic conditions, IκB kinase (IKK) activity is induced through a calcium/calmodulin-depend...

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Bibliografiske detaljer
Main Authors: Culver, Carolyn, Sundqvist, Anders, Mudie, Sharon, Melvin, Andrew, Xirodimas, Dimitris, Rocha, Sonia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950552/
https://ncbi.nlm.nih.gov/pubmed/20696840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00409-10
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