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Mechanism of Hypoxia-Induced NF-κB

NF-κB activation is a critical component in the transcriptional response to hypoxia. However, the underlying mechanisms that control its activity under these conditions are unknown. Here we report that under hypoxic conditions, IκB kinase (IKK) activity is induced through a calcium/calmodulin-depend...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Culver, Carolyn, Sundqvist, Anders, Mudie, Sharon, Melvin, Andrew, Xirodimas, Dimitris, Rocha, Sonia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950552/
https://ncbi.nlm.nih.gov/pubmed/20696840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00409-10
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