Mechanism of Hypoxia-Induced NF-κB

NF-κB activation is a critical component in the transcriptional response to hypoxia. However, the underlying mechanisms that control its activity under these conditions are unknown. Here we report that under hypoxic conditions, IκB kinase (IKK) activity is induced through a calcium/calmodulin-depend...

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Bibliografiska uppgifter
Huvudupphovsmän: Culver, Carolyn, Sundqvist, Anders, Mudie, Sharon, Melvin, Andrew, Xirodimas, Dimitris, Rocha, Sonia
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950552/
https://ncbi.nlm.nih.gov/pubmed/20696840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00409-10
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