Evolutionary Conserved Regulation of HIF-1β by NF-κB

Hypoxia Inducible Factor-1 (HIF-1) is essential for mammalian development and is the principal transcription factor activated by low oxygen tensions. HIF-α subunit quantities and their associated activity are regulated in a post-translational manner, through the concerted action of a class of enzyme...

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Bibliographic Details
Main Authors: van Uden, Patrick, Kenneth, Niall S., Webster, Ryan, Müller, H. Arno, Mudie, Sharon, Rocha, Sonia
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029248/
https://ncbi.nlm.nih.gov/pubmed/21298084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001285
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