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The origin of interstitial myofibroblasts in chronic kidney disease

Chronic kidney diseases (CKD), independent of their primary cause, lead to progressive, irreversible loss of functional renal parenchyma. Renal pathology in CKD is characterized by tubulointerstitial fibrosis with excessive matrix deposition produced by myofibroblasts. Because blocking the formation...

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Detalhes bibliográficos
Main Authors: Grgic, Ivica, Duffield, Jeremy S., Humphreys, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116994/
https://ncbi.nlm.nih.gov/pubmed/21311912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-011-1772-6
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