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The origin of interstitial myofibroblasts in chronic kidney disease

Chronic kidney diseases (CKD), independent of their primary cause, lead to progressive, irreversible loss of functional renal parenchyma. Renal pathology in CKD is characterized by tubulointerstitial fibrosis with excessive matrix deposition produced by myofibroblasts. Because blocking the formation...

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Autors principals: Grgic, Ivica, Duffield, Jeremy S., Humphreys, Benjamin D.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116994/
https://ncbi.nlm.nih.gov/pubmed/21311912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-011-1772-6
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