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The origin of interstitial myofibroblasts in chronic kidney disease

Chronic kidney diseases (CKD), independent of their primary cause, lead to progressive, irreversible loss of functional renal parenchyma. Renal pathology in CKD is characterized by tubulointerstitial fibrosis with excessive matrix deposition produced by myofibroblasts. Because blocking the formation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grgic, Ivica, Duffield, Jeremy S., Humphreys, Benjamin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116994/
https://ncbi.nlm.nih.gov/pubmed/21311912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-011-1772-6
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