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The origin of interstitial myofibroblasts in chronic kidney disease

Chronic kidney diseases (CKD), independent of their primary cause, lead to progressive, irreversible loss of functional renal parenchyma. Renal pathology in CKD is characterized by tubulointerstitial fibrosis with excessive matrix deposition produced by myofibroblasts. Because blocking the formation...

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Main Authors: Grgic, Ivica, Duffield, Jeremy S., Humphreys, Benjamin D.
格式: Artigo
語言:Inglês
出版: 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116994/
https://ncbi.nlm.nih.gov/pubmed/21311912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-011-1772-6
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