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Generation of novel radiolabeled opiates through site-selective iodination

Tritiated opioid radioligands have proven valuable in exploring opioid binding sites. However, tritium has many limitations. Its low specific activity and limited counting efficiency makes it difficult to examine low abundant, high affinity sites and its disposal is problematic due to the need to us...

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Bibliografische gegevens
Hoofdauteurs: Majumdar, Susruta, Burgman, Maxim, Haselton, Nathan, Grinnell, Steven, Ocampo, Julia, Pasternak, Anna Rose, Pasternak, Gavril W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115495/
https://ncbi.nlm.nih.gov/pubmed/21621410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.05.008
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