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Allosteric Inhibitor Development Targeting HIV-1 Integrase
HIV-1 integrase (IN) is one of three essential enzymes for viral replication, and a focus of ardent antiretroviral drug discovery and development efforts. Diligent research has led to the development of the strand transfer specific chemical class of IN inhibitors, with two compounds from this group,...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115487/ https://ncbi.nlm.nih.gov/pubmed/21275045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201000443 |
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