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Allosteric Inhibitor Development Targeting HIV-1 Integrase

HIV-1 integrase (IN) is one of three essential enzymes for viral replication, and a focus of ardent antiretroviral drug discovery and development efforts. Diligent research has led to the development of the strand transfer specific chemical class of IN inhibitors, with two compounds from this group,...

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Detaylı Bibliyografya
Asıl Yazarlar: Al-Mawsawi, Laith Q., Neamati, Nouri
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115487/
https://ncbi.nlm.nih.gov/pubmed/21275045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201000443
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