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Allosteric Inhibitor Development Targeting HIV-1 Integrase

HIV-1 integrase (IN) is one of three essential enzymes for viral replication, and a focus of ardent antiretroviral drug discovery and development efforts. Diligent research has led to the development of the strand transfer specific chemical class of IN inhibitors, with two compounds from this group,...

詳細記述

保存先:
書誌詳細
主要な著者: Al-Mawsawi, Laith Q., Neamati, Nouri
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115487/
https://ncbi.nlm.nih.gov/pubmed/21275045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201000443
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