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Allosteric Inhibitor Development Targeting HIV-1 Integrase

HIV-1 integrase (IN) is one of three essential enzymes for viral replication, and a focus of ardent antiretroviral drug discovery and development efforts. Diligent research has led to the development of the strand transfer specific chemical class of IN inhibitors, with two compounds from this group,...

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Sonraí Bibleagrafaíochta
Main Authors: Al-Mawsawi, Laith Q., Neamati, Nouri
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115487/
https://ncbi.nlm.nih.gov/pubmed/21275045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201000443
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