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Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways
Ion cotransporters, such as the Na(+)/Cl(−) cotransporter (NCC), control renal salt re-absorption and are regulated by the WNK-signalling pathway, which is over-stimulated in patients suffering from Gordon's hypertension syndrome. Here, we study the regulation of the NKCC2 (SLC12A1) ion cotrans...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114804/ https://ncbi.nlm.nih.gov/pubmed/21321328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.077230 |
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