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Highly Diastereoselective Chelation-controlled Additions to α-Silyloxy Ketones

The polar Felkin-Anh, Cornforth, and Cram-chelation models predict that the addition of organometallic reagents to silyl–protected α–hydroxy ketones proceeds via a non-chelation pathway to give anti-diol addition products. This prediction has held true for the vast majority of additions reported in...

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Autors principals: Stanton, Gretchen R., Koz, Gamze, Walsh, Patrick J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112462/
https://ncbi.nlm.nih.gov/pubmed/21534530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja201629d
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