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Diastereoselective Chelation-Controlled Additions to β-Silyloxy Aldehydes

[Image: see text] A general diastereoselective method for the addition of dialkylzincs and (E)-di and (E)-trisubstituted vinylzinc reagents to β-silyloxy aldehydes is presented. This method employs alkyl zinc triflate and nonaflate Lewis acids and affords chelation-controlled products (6:1 to > 2...

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Detalhes bibliográficos
Main Authors: Stanton, Gretchen R., Kauffman, Meara C., Walsh, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401491/
https://ncbi.nlm.nih.gov/pubmed/22721430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301354w
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