Pathogen Recognition Receptor Signaling Accelerates Phosphorylation-Dependent Degradation of IFNAR1

An ability to sense pathogens by a number of specialized cell types including the dendritic cells plays a central role in host's defenses. Activation of these cells through the stimulation of the pathogen-recognition receptors induces the production of a number of cytokines including Type I int...

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Bibliographic Details
Main Authors: Qian, Juan, Zheng, Hui, HuangFu, Wei-Chun, Liu, Jianghuai, Carbone, Christopher J., Leu, N. Adrian, Baker, Darren P., Fuchs, Serge Y.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111542/
https://ncbi.nlm.nih.gov/pubmed/21695243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002065
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