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Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1.

An ability to sense pathogens by a number of specialized cell types including the dendritic cells plays a central role in host's defenses. Activation of these cells through the stimulation of the pathogen-recognition receptors induces the production of a number of cytokines including Type I int...

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Bibliografiske detaljer
Main Authors: Juan Qian, Hui Zheng, Wei-Chun Huangfu, Jianghuai Liu, Christopher J Carbone, N Adrian Leu, Darren P Baker, Serge Y Fuchs
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2011-06-01
Serier:PLoS Pathogens
Online adgang:http://europepmc.org/articles/PMC3111542?pdf=render
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