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A novel fully human antitumour immunoRNase targeting ErbB2-positive tumours
BACKGROUND: ErbB2 is an attractive target for immunotherapy, as it is a tyrosine kinase receptor overexpressed on tumour cells of different origin, with a key role in the development of malignancy. Trastuzumab, the only humanised anti-ErbB2 antibody currently used in breast cancer with success, can...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111160/ https://ncbi.nlm.nih.gov/pubmed/21559015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.146 |
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