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A human, compact, fully functional anti-ErbB2 antibody as a novel antitumour agent
A new human, compact antibody was engineered by fusion of a human, antitumour ErbB2-directed scFv with a human IgG1 Fc domain. Overexpression of the ErbB2 receptor is related to tumour aggressiveness and poor prognosis. This new immunoagent meets all criteria for a potential anticancer drug: it is h...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747711/ https://ncbi.nlm.nih.gov/pubmed/15305184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602110 |
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