Two novel human anti-ErbB2 immunoagents are active on trastuzumab-resistant tumours

BACKGROUND: Overexpression of ErbB2 receptor in breast cancer is associated with disease progression and poor prognosis. Trastuzumab, the only humanised anti-ErbB2 antibody currently used in breast cancer, has proven to be effective; however, a relevant problem for clinical practice is that a high f...

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Main Authors: Gelardi, T, Damiano, V, Rosa, R, Bianco, R, Cozzolino, R, Tortora, G, Laccetti, P, D'Alessio, G, De Lorenzo, C
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2010
主題:
Translational Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822937/
https://ncbi.nlm.nih.gov/pubmed/20051960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605499
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