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Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs
We investigated the antitumour effect and ability to overcome the resistance to anti-EGFR drugs of enzastaurin, an inhibitor of VEGFR-dependent PKCβ signalling. Enzastaurin was evaluated alone and in combination with the EGFR inhibitor gefitinib, on growth and signalling protein expression in human...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527788/ https://ncbi.nlm.nih.gov/pubmed/18665191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604493 |
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