Inhibition and Covalent Modification of Tyrosine Hydroxylase by 3,4-Dihydroxyphenylacetaldehyde, a Toxic Dopamine Metabolite

Parkinson's disease (PD) is a neurodegenerative disorder marked by the selective loss of dopaminergic neurons, leading to a decrease of the neurotransmitter dopamine (DA). DA is metabolized by monoamine oxidase to 3,4-dihydroxyphenyacetaldehyde (DOPAL). While the mechanism of pathogenesis of PD...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Mexas, Lydia M., Florang, Virginia R., Doorn, Jonathan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109233/
https://ncbi.nlm.nih.gov/pubmed/21514317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2011.03.013
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky