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Catechol and Aldehyde Moieties of 3,4-Dihydroxyphenylacetaldehyde Contribute to Tyrosine Hydroxylase Inhibition and Neurotoxicity

Parkinson's disease (PD) is a progressive neurodegenerative disorder which leads to the selective loss of dopaminergic neurons. This causes a decrease in the important neurotransmitter dopamine (DA), which is essential for coordinated movement. Previous studies have implicated the monoamine oxi...

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Bibliografiske detaljer
Main Authors: Vermeer, Lydia M. M., Florang, Virginia R., Doorn, Jonathan A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428502/
https://ncbi.nlm.nih.gov/pubmed/22877852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.07.048
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