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Expression and Iron-Dependent Regulation of Succinate Receptor GPR91 in Retinal Pigment Epithelium
PURPOSE. GPR91, a succinate receptor, is expressed in retinal ganglion cells and induces vascular endothelial growth factor (VEGF) expression. RPE also expresses VEGF, but whether this cell expresses GPR91 is not known. Excessive iron is also proangiogenic, and hemochromatosis is associated with iro...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109050/ https://ncbi.nlm.nih.gov/pubmed/21357408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6722 |
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