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Loss of Heterozygosity Analysis Using Whole Genome Amplification, Cell Sorting, and Fluorescence-Based PCR

Loss of heterozygosity (LOH) is a common genetic lesion found in many human neoplasms. Extending investigation of LOH to large-scale clinical and public health science studies has proven difficult because of the small size and cellular and genetic heterogeneity of human neoplasms, in addition to the...

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Autori principali: Paulson, Thomas G., Galipeau, Patricia C., Reid, Brian J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC310769/
https://ncbi.nlm.nih.gov/pubmed/10330128
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