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Direct Inference of SNP Heterozygosity Rates and Resolution of LOH Detection
Single nucleotide polymorphisms (SNPs) have been increasingly utilized to investigate somatic genetic abnormalities in premalignancy and cancer. LOH is a common alteration observed during cancer development, and SNP assays have been used to identify LOH at specific chromosomal regions. The design of...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2098867/ https://ncbi.nlm.nih.gov/pubmed/18052545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030244 |
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