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Translation of an STR-based biomarker into a clinically compatible SNP-based platform for loss of heterozygosity
Loss of heterozygosity (LOH) has been shown to be a promising biomarker of cancer risk in patients with premalignant conditions. In this study we describe analytical validation in clinical biopsy samples of a SNP-based pyrosequencing panel targeting regions of LOH on chromosomes 17p and 9p including...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861428/ https://ncbi.nlm.nih.gov/pubmed/19407369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CBM-2009-0618 |
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