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Translation of an STR-based biomarker into a clinically compatible SNP-based platform for loss of heterozygosity

Loss of heterozygosity (LOH) has been shown to be a promising biomarker of cancer risk in patients with premalignant conditions. In this study we describe analytical validation in clinical biopsy samples of a SNP-based pyrosequencing panel targeting regions of LOH on chromosomes 17p and 9p including...

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Hlavní autoři: Kissel, Heather D., Galipeau, Patricia C., Li, Xiaohong, Reid, Brian J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861428/
https://ncbi.nlm.nih.gov/pubmed/19407369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CBM-2009-0618
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