Copy Number and Loss of Heterozygosity Detected by SNP Array of Formalin-Fixed Tissues Using Whole-Genome Amplification

The requirement for large amounts of good quality DNA for whole-genome applications prohibits their use for small, laser capture micro-dissected (LCM), and/or rare clinical samples, which are also often formalin-fixed and paraffin-embedded (FFPE). Whole-genome amplification of DNA from these samples...

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Main Authors: Stokes, Angela, Drozdov, Ignat, Guerra, Eliete, Ouzounis, Christos A., Warnakulasuriya, Saman, Gleeson, Michael J., McGurk, Mark, Tavassoli, Mahvash, Odell, Edward W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180289/
https://ncbi.nlm.nih.gov/pubmed/21966361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024503
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